Here's a portion of a longer post I made on pistol-forum, didnt want to re-type it all. Imho for conus le use the 320 would be my #1 choice for a striker.
This may get a little long winded, but.. I started my career with a 226 and it is what I learned to shoot on so I may be bias. My first department had a very open weapon policy (Pretty much any caliber from major manufacturer HK/Sig/Glock/Smith 9/40/45/357) so when all my buddies were going plastic I thought that I was missing the train and jumped on myself. I went to a G21 and then a G17 and carried that for several years until my current department that at the time only allowed M&P's. The M&P is a whole other thread, but suffice to say it wasn't for me. My PD recently approved the 320 and 226/220, but only if you attended a striker to hammer conversion course, if you currently carried striker (M&P) you could switch to the 320 which I did the day after the policy came out (switch was more about getting away from the M&P than switching to the 320. Would have switched to Glock if that was the only other option)
To back track a bit, I've always had issues with strikers shooting left (all my glocks and M&P) not a ton, but enough to irritate me (hitting the 9 instead of x at 10 yds). I initially had the same problem with the 320 until I switched to the large size module. With the large module I'm dead on like with my 226's. I put around 5K through my full size 320 and can't recall a single malfunction (all factory ammo, either AE or WWB). The only negative I can mention about the pistol is lack of back end support. Ordering spare/replacement parts is very difficult as they are somewhat new. I have had 0 issues with finding holsters and Safariland offers both the 6360 and 6378 so covered there. For me, it came down to it being so new with not enough track record or part availability. I am not aware of any issues from officers at our PD and many are switching over. Glocks were also recently approved and the 320 is still the popular choice. If you like strikers and aren't bothered by the lack of spare parts I'd say go for it. I was 100% confident carrying it on duty. Side note, my preference is for the carry size and if that is an option I would go that way. The compact slide has a dual recoil spring and for me tracks flatter and transitions easier.